The most effective way to begin would be to Buy RS Gold do some questing - similar to as with most of the abilities. Easy missions like The Restless Ghost, Priest in Peril, Holy Grail, and Recruitment Drive will be there to take you through the basics of Prayer skills. Once you have completed this you'll need to be able to harvest bones to get higher levels of Prayer.

An excellent source of Prayer earnings is Dragon Killing. The bones of Dragon Killers provide significant experience and don't require an extremely high level of skills. To eliminate Blue Dragons below the Taverley in Taverley Dungeon you do not require a lot of resources at all since they can be killed from a safe location. 

If you're planning to do this, keep in mind to do it with Magic since they're weak to this specific style of fighting. Utilize giant eggs, rocks and columns to get Dragon stuck, and then finish them off with your spells.

Additionally, you can kill Green Dragons north of the Graveyard in the Wilderness. Simply bring an Anti-Dragon Shield, food and equipment. Avoid taking anything valuable so that you don't risk losing an account on Player Killers. It's also worth considering farming on Void Knight Equipment because you will not lose it losing it in low Wilderness. This is a superb option suitable for Dragon Killing and a safe one for wearing in this zone.

All bones you collect should be sacrificed on RuneScape Gold 2007 the Chaos Altar, but it isn't a good idea and you should not take anything besides the bones that you want to sacrifice. This is one of the most Player Active zones on Runescape It is located on level 38 of Wilderness.