Pure Micronized Trans Resveratrol Powder
Over 99% pure Pure Micronized Trans Resveratrol powder supplement
Independently lab tested
100% Natural, Non-GMO
Gluten-Free, vegan and allergy friendly
Free 0.50ml scoop with every order
Free UK delivery on all orders
Resveratrol has been found to possess numerous potential health-related benefits including:
Lowering cholesterol
Protecting heart and circulatory system
Protects the brain
Helps to lower blood sugar levels
Increases Insulin Sensitivity
About Resveratrol:
Resveratrol is a naturally occurring compound called a polyphenol and is present in a number of common food items such as berries, grapes, vine, peanuts, etc. Plants that produce resveratrol do so partly as a protective mechanism and response to stressors within their environments, including the presence of insects or other predators, damage, injury, and fungal varieties. Resveratrol is believed to be one of the most potent polyphenols and a strong protector against aging and free radical damage.
The benefits of resveratrol were first discovered when researchers established that a variety of yeasts, microbes, insects and animals that were fed resveratrol experienced an increased lifespan. Several studies continued to confirm these longevity and anti-aging benefits, in their successful work on flies, fish, mice and nematode worms, all of which lived longer compared to control groups that were not treated with this phytonutrient.
Being a part of the polyphenol group, Resveratrol possesses antioxidant properties that are believed to help prevent the formation of cancerous cells.
How Does Resveratrol Work?
Resveratrol works as anti-oxidant and fights free radicals which contribute towards increased aging. Resveratrol can either passively cross cell membranes or interact with its receptors due to its unique physical and chemical properties, making it possible for Resveratrol to interact with inter and extracellular molecules effortlessly. It is because of this that its mechanism of action is triggered by one of the two means (at a cellular level):
By developing its effect inside the nucleus
Activating intracellular mechanism by first activating signalled pathways when binding to receptors of the cell membrane
The way it functions as an anti-aging substance can possibly be explained how it activates SIRT. A study suggests that it can directly activate NMNAT enzyme which increases the intracellular activity and levels of NAD+ which is likely to affect SIRT which primarily requires the presence of NAD+ in order to function. In another experiment, human cells were treated with Resveratrol independent of NMNAT enzyme. Even without the presence of NMNAT, Resveratrol still rejuvenated old cells which started to divide and develop longer telomeres with the restoration of the splicing factor expression. The cells not only started to appear younger but behaved more like younger cells as well.
Our Pure Resveratrol powder supplement is more than 99% pure as tested by a 3rd party laboratory. To get an even better price for our Pure Resveratrol powder you can subscribe and save with our monthly subscription service or, for the very best price per gram, buy in bulk quantities.
Experts view:
Dr Brad Stanfield talks about Resveratrol including how to take and store it.
Dosage and Guidelines:
Initial Precaution:
It is advised to all the individuals taking Resveratrol for the first time to start with a low dose to determine whether the product suits them or if their body is reacting against it (it is highly unlikely and no such cases have been recorded). The first dose should not exceed more than 125mg (taken as per the directions indicated on the packaging) and then monitor for possible adverse side-effects or reactions which are very unlikely and have never been observed.
Directions for Regular Use:
There are multiple research papers into the optimum method of absorption of Resveratrol and no current consensus on the best way to take it. Amongst the various papers, it has been observed that Resveratrol’s bioavailability can be improved when consumed with a food that has an element of fat content. This observation is complementary to Dr David Sinclair’s approach which is to take Resveratrol with yoghurt at breakfast. This paper explores the various studies on intake options. Other studies, also included in the aforementioned paper, have indicated taking Resveratrol with green tea will enhance its effects and is best taken on an empty stomach.
Recommended Daily Dosage:
0.5 grams per day.
Upper Dosage (Depending upon the age and other factors):
2 grams per day.
Note:
If you are on prescribed medication or have been medicating for a long term previously, then it is best to consult with your doctor before starting with Resveratrol.
Storage:
Keep the contents in the provided packaging or an airtight glass jar. Keep away from sunlight and avoid exposure to a temperature above 24 degrees Celsius. Keep in a cool dry place and don’t expose the contents to moisture. This product can be kept in a fridge or refrigerator.
Store your Pure Resveratrol Powder in our dark amber glass jars to ensure no air or contaminants are exposed to your supplements
Our Packaging:
Longevity Box Pure Resveratrol Powder is provided and supplied in re-sealable food-graded/food-safe pouches/bags that are transparent on one side. It is recommended that this transparent-sided pouch/bag is stored in another bag/pouch to prevent any moisture or light from entering the transparent-sided pouch. It is advised to keep the clear-sided bad/pouch in this protective bag/pouch at all times.
A measuring spoon is provided that carries 125 mg Resveratrol powder when levelled.
Extra scooping spoons can also be purchased from the website. Bigger spoons that can scoop 250 mg Resveratrol powder are also available for our valued customers.
We also have specially-darkened glass jars available for keeping Resveratrol powder. These jars can contain up to 50g Resveratrol powder, are re-sealable, and airtight.
References and Further Readings:
For the convenience of the customers and enthusiasts, listed below are several links for references. Please keep in mind that none of the sources listed below is affiliated with Longevity Box in any way, nor did they use our Pure Resveratrol Powder in their studies. For video resources, you can watch this video (duration 57 minutes). Other resources include:
https://pubmed.ncbi.nlm.nih.gov/12939617/
Howitz, K.T., Bitterman, K.J., Cohen, H.Y., Lamming, D.W., Lavu, S., Wood, J.G., Zipkin, R.E., Chung, P., Kisielewski, A., Zhang, L.L. and Scherer, B., 2003. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature, 425(6954), pp.191-196.
https://www.ajevonline.org/content/43/1/49
Siemann, E.H. and Creasy, L.L., 1992. Concentration of the phytoalexin resveratrol in wine. American Journal of Enology and Viticulture, 43(1), pp.49-52.
https://podcastnotes.org/joe-rogan-experience/sinclair/
Podcast Notes. 2021. The Joe Rogan Experience - David Sinclair, Ph.D. • Podcast Notes. [online] Available at: <https://podcastnotes.org/joe-rogan-experience/sinclair/> [Accessed 1 February 2021].
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0090131
Blanchard, O.L., Friesenhahn, G., Javors, M.A. and Smoliga, J.M., 2014. Development of a lozenge for oral transmucosal delivery of trans-resveratrol in humans: proof of concept. PloS one, 9(2), p.e90131.
https://academic.oup.com/biomedgerontology/article/73/1/21/3063060
En.wikipedia.org. 2021. Sublingual administration. [online] Available at: <https://en.wikipedia.org/wiki/Sublingual_administration> [Accessed 1 February 2021].
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963347/
Stockinger, J., Maxwell, N., Shapiro, D., deCabo, R. and Valdez, G., 2018. Caloric restriction mimetics slow aging of neuromuscular synapses and muscle fibers. The Journals of Gerontology: Series A, 73(1), pp.21-28.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880862/
Timmers, S., Konings, E., Bilet, L., Houtkooper, R.H., van de Weijer, T., Goossens, G.H., Hoeks, J., van der Krieken, S., Ryu, D., Kersten, S. and Moonen-Kornips, E., 2011. Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. Cell metabolism, 14(5), pp.612-622.
Disclaimers:
It is advised to use this product at your own discretion. Resveratrol mass-production started in 2000 and long-term effects on humans are yet to be determined.
This is just a supplement and should not be considered as an alternative for a varied diet.
Consult with your doctor before incorporating it into your daily routine.
In the test-tube analysis, Resveratrol has been found to inhibit platelet aggregation; higher intake with blood thinners and anticoagulants may cause bruising or bleeding.
Research around Resveratrol is still ongoing and as more is discovered about Resveratrol, the content on the website may get updated or changed altogether.
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