DermiSolve Skin Tag Serum For those looking for immediate results, and aren't afraid of a little pain, there is another option. Quite simply, you can cut the skin tag off. If possible, tie the tag off at its base with thread or dental floss. Then use sterilized scissors or nail clippers to cut off the skin tag. Be sure you are prepared with peroxide or antibacterial ointment to clean the wound...